Can transport phenomena play an important part in the treatment of many different biological diseases? This impact has already been shown beyond doubt in the case of many hitherto intractable infections caused by bacteria and viruses. The power of living cells to transport drugs and other therapeutic agents over their own external cell membranes has been the subject of numerous reports. In parallel, processes in which cells enable themselves to take apart or make new molecules in order to repair tissue have attracted considerable interest. In recent years, it has been realized that hydrodynamic coupling can become relevant in neuro-plasticity, developmental processes and in the steady state.
The question is therefore whether the knowledge of transport phenomena can be used to treat, or to avoid, certain of the more common diseases in a biological context. The chapters in this textbook are devoted to the biological transport and kinetics of small ions, proteins and of drugs, and are intended to shed light on the mechanisms of not only the transport but of the kinetics of this transport as well. We will therefore consider the influence of the net charge of the various transport systems and the arrangements of the charges on the transport mechanisms and kinetics in a variety of biological transport situations.
In this book the transport phenomena in biological systems with its emphasis on molecular kinetics has three objectives : firstly, to consider the fundamentals of molecular transport in the biological systems, next, to examine the systems of diseases where this transport is significant in their genesis and treatment, and finally, to introduce the reader to the biological transport problem in a general sense. Biophysics is used as a bridge between the two disciplines of biology and chemistry. While the 'biology' is concerned with the nature of the biological system, the 'chemistry' relates to the nature of the chemical species involved in the transport. d2c66b5586